PhD Student
Position - C. elegans Arrhythmia model - Optogenetics
and Molecular Biology
For a European
Union funded project on cellular and molecular mechanisms of arrhythmia, we
seek a highly motivated student for a PhD project, starting immediately, for up
to 4 years. Using advanced methods for gene targeting and transgene
construction, candidate mutations inducing muscle arrhythmia will be introduced
in the animal model Caenorhabditis elegans. Furthermore, optogenetic
methods, using e.g. Channelrhodopsin to photoinduce arrhythmia, will be used.
A university
degree (Diploma, Master) in molecular biology, biology, biochemistry, or
physiology is required. Solid experience in molecular biology methods is a
prerequisite, previous experience with C. elegans, as well as with “recombineering” methods, is highly welcome. For more
information, see: EMBO J (2005) 24: 2566; Curr. Biol. (2005) 15: 2279; Nature (2007) 446: 633; Nat. Meth. (2008) 5: 895; EMBO J (2009) doi:10.1038/emboj.2009.204; and http://www.biochem.uni-frankfurt.de/gottschalk/index.html.
Send CV,
description of research experience and interests, certificates, and references
to A. Gottschalk, Goethe-University,