2004 West Coast Worm Meeting Program

PLATFORM TALKS

I. Databases, Genomics, and Proteomics
Saturday, August 21, 2004, 7:00-11:00 PM (Corwin Pavilion)

Kaveh Ashrafi and Diana Chu, session chairs

1. Searching Worm Literature for Information - Textpresso Makes it Easy!
   Eimear E. Kenny, Hans-Michael Mueller, Paul W. Sternberg

2. The C. elegans Knockout Consortium
   Mark Edgley, Gary Moulder, Julia Buckner, Owen Dadivas, Julie Farley, Angela Fisher, Kevin Grant, Candice Guscott, Bethany Hannafon, Allison Hay, Jeff Holmes, Peter Huang, Joanne Lau, Lucy Liu, Jason Maydan, Sheldon McKay, Nadereh Rezania, James Robertson, Beth Rogers, Bin Shen, Erica Simon, Robert Barstead, Don Moerman

3. Frogs and snails and puppy dog tails? Wormatlas launches a guide to what boy worms are made of
   Robyn Lints, Zeynep F. Altun, Huawei Weng, Gloria Stephney, Maurice Volaski, David H. Hall

4. High throughput measurement of protein expression in C. elegans
   Gennifer E. Merrihew, Michael MacCoss

5. Gene expression profiling of cells, tissues and developmental stages of C. elegans
   Donald G. Moerman, S. J. McKay, R. Johnsen, J. Khattra, D. Anastis, J. Asano, D.L., Baillie, S. Chan, L. Chen, B. Goszczynski, P. Huang, S.J.M. Jones, D. Li, A. Lorch, A., Mah, J. McGhee, C. Mills, R. Newbury, J. Perkins, A. Pouzyrev, D.L. Riddle, R., Schnabel, E. Tang, H. Tian, D. Tu, R. Viveiros, A. Warner, K. Wong, Z. Zhao, R. Zhapf, M. Marra

6. Global Identification of C. elegans Regulatory Motifs
   Yueyi I. Liu, Stuart K. Kim

7. Global profile of intestine-specific gene expression in C. elegans
   Florencia Pauli, Yueyi Liu , Stuart K. Kim

8. A gene expression profile of bodywall muscle cells
   Rebecca M. Fox, Stephen E. Von Stetina, Susan J. Ruff, Joan McDermott, Thomas Brodigan, Michael Krause, K. Wong, S. J. McKay, R. Johnsen, J. Khattra, D. Anastis, D.L. Baillie, S.J.M. Jones, R. Newbury, R. Viveiros, A. Warner, R. Zhapf, M. Marra, Don Moerman, David M. Miller III

9. Cellular identity of GABAergic Motor Neurons in C. elegans
   Hulusi Cinar, Sunduz Keles, Yishi Jin

10. Possible effect of chromatin structure on nhr family regulation
    Emily Rocke, Marc Van Gilst, Keith Yamamoto, James H. Thomas

11. Annotation of C. elegans genes associated with longevity using serial analysis of gene expression (SAGE)
    P. Ruzanov, S. J. McKay, S. J. M. Jones, M. A. Marra, D. G. Moerman, D. L. Baillie, D. L. Riddle

12. Identification of Genetic Biomarkers and Regulators of Aging in C. elegans
    Kendall Wu, Yueyi Liu, James Lund, John Wang, Min Jiang, Stuart Kim

13. Shared transcriptional signature in dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
    Joshua J. McElwee, Gene Schuster, Eric Blanc, Janet Thornton, James H. Thomas, David Gems

II. Aging and Disease Models
Sunday, August 22, 2004, 8:30 AM - 12:15 PM (Campbell Hall)

Brent Derry and Mako Saito, session chairs

14. Identification of longevity genes in C. elegans using a genome-wide RNAi library
    Malene Hanse, Ao-Lin Hsu, Andrew Dillin, Andrew Fraser, Ravi Kamath, Julie Ahringer, Cynthia Kenyon

15. Identification of Cells and Genes that Function in the Regulation of Lifespan by the Reproductive System
    Arjumand Ghazi, Sivan Henis-Korenblit, Cynthia Kenyon

16. Specifying the DAF-16 longevity network through SMK-1, a potential cofactor ofDAF-16
    Hui Ma, Suzanne Wolff, Hugo Aguilaniu, Pamela Woodring, Denise Burch, Gustavo Maciel,Tony Hunter, Andrew Dillin

17. The C. elegans p53 homologue, CEP-1, coordinates cell size in response to anoxia, and in conjuction with the Krit1 homologue ZK265.1
    A. Kristine Jolliffe, Fazl R. Molana, W. Brent Derry

18. CED-4-dependent apoptosis in icd-1 and icd-2 mutants involves a CED-3-independent caspase
    Tim A. Bloss, Joel H. Rothman

19. Knockout of GLT-3 C. elegans Glutamate Transporter: A Genetic Approach to Study Excitotoxic Neurodegeneration
    Itzhak Mano, Sarah Straud, Monica Driscoll

20. Calcium permeability of death-inducing DEG/ENaC ion channel MEC-4(d)
    Laura Bianchi, Beate Gerstbrein, Dewey Royal, Gargi Mukherjee, Jian Xue, Monica Driscoll

21. Exploring the role of alpha-synuclein, parkin, and the dopamine transporter in DA neuron degeneration in C. elegans models of Parkinson’s disease
    Marketa Marvanova, Garry Wong, Richard Nass

22. C. elegans Bardet-Biedl syndrome proteins link cilia dysfunction to obesity, blindness, cognitive impairment, kidney and heart problems
    Oliver E. Blacque, Chunmei Li, Michael J. Reardon, Stephen R. Wicks, Michel R. Leroux

23. Role of an acetylcholine transporter in a C. elegans model of muscular dystrophy
    Hongkyun Kim, Matthew J. Rogers, Janet E. Richmond, Steven L. McIntire

24. Characterization of a mutant affecting ADPKD Homologue Gene Expression and Male Mating
    Juan Wang, Maureen M Barr

25. A C. elegans RNAi screen identifies proteins that may contribute to human cardiac arrhythmia
    Christina I. Petersen, Franck Potet, Toni R. Grim, Ping Yang, Kenshi Hayashi, Dan M. Roden, James H. Thomas, Jeffrey R. Balser

26. Mutational analysis of genes disrupting neuronal synchrony in Caenorhabditis elegans
    Allyson V. McCormick, Gennifer E. Merrihew, James H. Thomas

III. Behavior
Sunday, August 22, 2004, 7:00 PM - 11:00 PM (Campbell Hall)

Rene Garcia and Karen Oegema, session chairs

27. The C. elegans Rho family guanine exchange factor VAV-1 regulates rhythmic contractions
    Ken Norman, Rob Fazzio, Jerry Mellem, Mary Beckerle, Villu Maricq

28. Signals downstream of the defecation clock require intercellular communication in the intestine
    Maureen A. Peters, Erik M. Jorgensen

29. A secretory protein OSM-7 expressed in hypodermis may regulate chemotaxis to sodium ion and resistance to high osmolarity
    Keiko Mase, Yasumi Ohshima, Takeshi Ishihara, Makoto Koga

30. Bilaterally asymmetric nature of the ASE chemosensory neuron
    Hiroshi Suzuki, Christian Froekjaer-Jensen, Tod R. Thiele, Shawn Lockery, William R. Schafer

31. G Protein-Coupled Receptor Kinase (GRK) Function is Required for Chemosensation in C. elegans
    Denise M. Ferkey, Hana S. Fukuto, Alfonso Apicella, Jr., Hannes Lans, Tahira Sharmeen,Wei Chen, Robert J. Lefkowitz, Gert Jansen, William R. Schafer, Anne C. Hart

32. C. elegans recognizes protons as a nociceptive stimulus through the DEG/EnaC and TRP channel
    Alfonso Apicella Jr., Robert D. Slone, Monica Discroll, William R. Schafer

33. A microfluidic aerotaxis device for studying oxygen response in C. elegans
    Hang Lu, Jesse M. Gray, David S. Karow, Andy J. Chang, Michael A. Marletta, Cornelia I. Bargmann

34. The LOV-2 Kinesin Acts in Dendrites and/or Cilia to Regulate Ciliary Receptor Localization and Male Mating Behavior
    Erik M Peden, Maureen M. Barr

35. Characterization of the sperm transfer step of male mating behavior of Caenorhabditis elegans
    Gary Schindelman, Allyson J. Whittaker, Jian Yuan Thum, Shahla Gharib, Paul W. Sternberg

36. Mapping a Navigational Circuit in C. elegans
    Jesse M. Gray, Joseph J. Hill, Cornelia I. Bargmann

37. Nematode locomotion: Integrating theory with genetic perturbations and comparative analysis
    Jan Karbowski, Christopher J. Cronin, Adeline Seah, Jane E. Mandel, Paul W. Sternberg

38. Swimming as a distinct form of locomotion in C. elegans: Analysis of the switch between crawling and swimming
    Jon Pierce-Shimomura, Steve McIntire

39. Opposing Functions of Calcineurin and CaMKII Regulate G-protein Signaling in Egg-laying Behavior of C. elegans
    Jungsoo Lee, Joohong Ahnn

40. Identification and characterization of calcineurin binding protein in C. elegans
    Changhoon Jee, Joohong Ahnn

IV. Pathogenesis and Cell Biology
Monday, August 23, 2004, 8:30 AM - 12:15 PM (Campbell Hall)

Danielle Garsin and Dan Starr, session chairs

41. Olfactory learning of C. elegans in response to pathogenic bacteria
    Yun Zhang, Hang Lu, Cornelia I. Bargmann

42. Regulatory mechanisms involved in the innate immune response of Caenorhabditis elegans to Pseudomonas aeruginosa infection revealed by genome scale gene expression analyses
    Michael Shapira, Brigham J. Hamlin, Marianne C. Campbell, Min Jiang, Stuart K. Kim, Man-Wah Ta

43. Beneficial and pathogenic interactions in the nematode gut: one bacterium, two interactions
    Todd A. Ciche, Paul W. Sternberg

44. DAF-16 Regulated Genes Mediate Resistance to Pathogens
    Violeta Chavez, Danielle A. Garsin

45. Through regulation of fat storage and metabolism, C. elegans nuclear hormone receptor nhr-49 facilitates an adaptive response to starvation and ensures normal longevity
    Marc Van Gilst, Amber Jolly, Haralambos Hadjivassiliou, Keith Yamamoto

46. eat-17 encodes a putative Rab GTPase activating protein that acts in concert with RAB-6.2 to promote proper grinder formation in C. elegans
    Sarah Straud Anselmo, Leon Avery

47. The vacuolar ATPase prevents inappropriate EFF-1-mediated cell fusion in the embryonic epidermis
    Kenji Kontani, Ivan P.G. Moskowitz, Joel H. Rothman

48. C. elegans condensin complex mediates chromosome compaction and chromatid restructuring during bivalent formation in meiosis
    Raymond C. Chan, Aaron F. Severson, Barbara J. Meyer

49. Dynamic localization of meiosis-specific structural proteins during SC disassembly and chiasma emergence
    Kentaro Nabeshima, Monica P. Colaiacovo, Anne M. Villeneuve

50. Centriole assembly requires both centriolar and pericentriolar material proteins
    Alex Dammermann, Thomas Müller-Reichert, Laurence Pelletier, Bianca Habermann, Arshad Desai, Karen Oegema

51. The double life of MEL-26
    Lionel Pintard, Sarah Glaser, Matthias Peter

52. Computer-assisted analyses reveal length-dependent pulling force as the primary mechanism for male pronuclear migration
    Akatsuki Kimura, Shuichi Onami

53. Expression of kinesin motor proteins during embryogenesis and neural function in C. elegans
    Shahid S. Siddiqui, Douglas Yau, Zhongying Zhao, M. Yusuf Ali, M. L. Khan, Shams T. Khan, Fumio Hori, Zeba K. Siddiqui, Robert Jhonsen, David Baillie, Asrar B. Malik

V. Development
Monday, August 23, 2004, 1:30 PM - 6:00 PM (Campbell Hall)

Morris Maduro and Jeb Gaudet, session chairs

54. Recruitment and spreading of the dosage compensation complex along X chromosomes
    Gyorgyi Csankovszki, Barbara J. Meyer

55. Multiple discrete cis-acting recruitment sites target X chromosomes for repression by the dosage compensation complex
    Patrick McDonel, Judith Jans, Barbara J. Meyer

56. Loss of BOX-1 bypasses the need for SDC-1 in dosage compensation
    Annie J. Lee, Barbara J. Meyer

57. The autosomal signal of sex determination
    Paola Nix, Margaret M. Jow, Jennifer R. Powell, Barbara J. Meyer

58. Sperm activation and male fertility in C. elegans
    Gillian Stanfield, Anne Villeneuve

59. The role of lin-35 and xnp-1/ATR-X in somatic gonad development
    Aaron M. Bender, Orion Wells, David S. Fay

60. The nuclear receptor NHR-25 directs cell shape dynamics during epidermal differentiation and interacts with the Wnt signaling
    Marie Silhankova, Marek Jindra, Marc Van Gilst, Masako Asahina

61. Role of Wnt and Notch signaling and Hox gene in the patterning of C. elegans hook sensillum competence group
    Hui Yu, Paul W. Sternberg

62. GLP-1/Notch and LIN-12/Notch-mediated repression involves the REF-1 family of bHLH proteins in C.elegans embryos
    Alexandre Neves, James R. Priess

63. Neuronal Cell Fate Specification at the Synapse by Lateral Signaling and the TIR Protein NSY-2
    Chiou-Fen Chuang, Alvaro Sagasti, Cori I. Bargmann

64. Trans-splicing and polyadenylation of let-7 microRNA primary transcripts
    John Bracht, Shaun Hunter, Rachel Eachus, Phillip Weeks, Amy E. Pasquinelli

65. Genome-wide analysis of pharynx development
    Pliny A. Smith, Chris Armstrong, Dirk McMurray, Tala Fakhouri, Mike Overfield, Marc Vidal, Susan E. Mango

66. Analysis of pel-2, a gene required for coordination of pharynx and epidermal development
    Kelly A. Harradine, Renaud Legouis, Joel H. Rothman

67. PHA-4 and DAF-12 modulate foregut growth and remodelling
    Wanyuan Ao , Jeb Gaudet, Jim Kent, Srikanth Muttumu, Susan Mango

68. The DAF-12 complex: A molecular switch whose outcome depends on the relative abundance of its components?
    Gemma Brown, Jie Li, Samuel Lee, James H. Thomas

VI. Neurobiology
Tuesday, August 24, 2004, 8:30 PM - 12:15 PM (Campbell Hall)

Kang Shen and Noelle L’etoile, session chairs

69. Wnt signaling in antero-posterior neuronal migration and axon guidance
    James B. Endres, Chun-Liang Pan, Gian Garriga

70. Wnt signals regulate neuronal polarity and position of antero-posterior axon outgrowth in C.elegans
    Massimo A. Hilliard, Cori Bargmann

71. The C.elegans kinesin-like VAB-8 protein acts with UNC-40/DCC and SAX-3/ROBO to guide axons posteriorly
    Natsuko Watari-Goshima, Naomi Levy-Strumpf, Joseph G. Culotti, Gian Garriga

72. Talin functions in neuronal axon guidance through integrin signaling in C. elegans
    Chris D. Suh, Scott Clark, Alexandr Gonchrov, Cori Bargmann, Yishi Jin

73. Mechanosensory neurite termination and tiling are directed by sax-2 and the sax-1 kinase
    Maria E. Gallegos, Cori I. Bargmann

74. Spaced stimulation during development has profound effects on the structure and function of the nervous system
    Celia M. Holmes, Catharine H. Rankin

75. Why are most neurons in the head?
    Beth L. Chen, David H. Hall, Dmitri B. Chklovskii

76. Fluoxetine competes with serotonin to control movement
    Catherine M. Dempsey, Anahid E. Powell, Ji Ying Sze

77. Role of the C. elegans tomosyn homolog (TOM-1) in synaptic transmission
    Andrea M. Holgado, Elena Gracheva, Mike Nonet, Gayla Hadwiger, Janet E. Richmond

78. acr-16 mutants eliminate the non-levamisole acetylcholine response in C. elegans body wall muscles
    Denis V.Touroutine, Rebecca M. Fox, David M Miller, III, Janet E. Richmond

79. LEV-9 encodes a putative protein in the sarcoglycan complex
    Adam W. Tearle, Suchitra Jagannathan, William R. Schafer

80. The major function of UNC-31 (CAPS) - mediated secretion is to activate the GSA-1 (Gs ) pathway of the synaptic signaling network
    Nicole K. Reynolds, Michael A. Schade, Kenneth G. Miller

81. Voltage clamp recordings from pharyngeal muscle confirm the roles of EGL-19 and EXP-2 and uncover a novel function for the T-type Ca channel CCA-1
    Boris Shtonda, Katherine Steger, Leon Avery

WORKSHOPS

Sunday, August 22, 2004 1:30 - 5:40 PM (Multi-Cultural Theater)

1:30 PM RNAi techniques and screens

Andrew Dillin and Amy Pasquinelli, organizers

2:20 PM Bioinformatics and databases

Erich Schwarz, organizer

3:10 PM Gene expression and microarrays

Coleen Murphy and Marc van Gilst, organizers

4:00 PM Behavioral analysis

Chris Cronin, organizer

4:50 PM Education

Greg Hermann, organizer

POSTERS

Sunday, August 22, 2004 1:30 PM – 5:30 PM (Corwin Pavilion)

82. The State of the WormBase: 2004
    Erich M. Schwarz, Paul W. Sternberg, WormBase Consortium

83. WormBook- An Online Review of C. elegans Biology
    Lisa Girard, Juancarlos Chan, Eimear Kenny, Paul Sternberg, Lincoln Stein, Marty Chalfie

84. Predicting genetic interactions by multi-source data integration
    Weiwei Zhong, Paul Sternberg

85. A Bayesian approach toward analyzing the network of genes involved in C. elegans programmed cell death
    Chao-I Chen, S. Rao Jammalamadaka, Xiaofang Lei, Vebjorn Ljosa, Thomas A. McCloskey, Joel H. Rothman, Ambuj K. Singh, and Chiou-Wei Tsai

86. Evaluation of Metrics for Cross-species Conservation of Noncoding Sequence in Nematodes
    Alok J Saldanha, Daniel Xun Fu, Paul W Sternberg

87. Experimental annotation of C. elegans and C. briggsae genomes by the TEC-RED technique
    Byung Joon Hwang, Hans-Michael Muller, Sheldon McKay, Peter Huang, Shahla Gharib, Steven Jones, Marco Marra, Don Moerman, David Baillie, Paul W. Sternberg

88. Identification of Regulatory Elements in Caenorhabditis elegans using Orthology Biased Gibbs Sampling
    Keith A Boroevich, David L Baillie, Steven JM Jones

89. Studying Hypoxia Using C. elegans Microarrays
    Meghann E. Mabon, C. Michael Crowder

90. Finding unc-4 Target Genes
    Rebecca M. Fox, Stephen E. Von Stetina, Kathie Watkins, Kellen Olszewski, Clay Spencer, Joseph D. Watson, Denis Dupuy, Marc Vidal, David M. Miller, III

91. Genomic strategies to identify synaptic specificity genes regulated by the UNC-4 homeodomain transcription factor
    Stephen E. Von Stetina, Rebecca M. Fox, Joseph D. Watson, David M. Miller, III

92. An mRNA-tagging strategy to profile gene expression in the nervous system.
    Stephen E. Von Stetina, Rebecca M. Fox, Joseph D. Watson, Clay Spencer, Kellen Olszewski, Peter J. Roy, Denis Dupuy, Marc Vidal, Stuart K. Kim, David M. Miller, III

93. Transcription profiling of C. elegans developmental stages using serial analysis of gene expression and microarrays
    K. Wong, S. J. McKay, D. L. Baillie, S. J. M. Jones, M. A. Marra, C. Mills, P. Huang, P. Ruzanov, D.G. Moerman

94. Investigation of transcriptional activity in C. elegans using Fluorescent Timer©
    Allan K. Mah, Domena K. Tu, John R. Tyson, Robert C. Johnsen, David L. Baillie

95. A novel method for tissue-specific profiling of genes in C. elegans
    William J. Michels

96. Expression in C. elegans of promoter::GFP constructs for genes with human orthologs
    R. Johnsen, D. Anastis, L. Chen, A. Mah, S. Mckay, R. Newbury, E. Tang, D. Tu, R. Viveiros, K. Wong, Z. Zhao, S. Jones, M. Marra, D. Moerman, E. Sonnhammer, D. Baillie

97. Proteome analysis and protein expression profiling of wild-type Caenorhabditis elegans using mass spectrometry.
    Aruna Somasiri, D.Smith, J. Haddow, R. Olafson, D.L. Baillie, S.J.M. Jones, D.G. Moerman

98. Identification of Novel Drug Targets through Functional Characterization of Conserved, Pharmaceutically Tractable, Proteins in Caenorhabditis elegans
    Christopher Shelton, Megan McLaughlin, Yun Liu, Junping Jing, George Livi, Caretha Creasy

99. Identification of alternative splicing regulatory elements in C. elegans
    Jennifer L. Kabat, Hiram Clawson, Paul McKenna, Alan M. Zahler

100. Reporter-based investigation of miRNA regulation
     Shaun E Hunter, Amy E Pasquinelli

101. Heritable Silencing triggered by RNAi
     Rosa Alcazar, Andy Fire

102. Investigation of RNA-dependent RNA polymerase function during RNA interference
     Julia Pak, Andrew Z. Fire

103. Context dependant interactions in RNAi
     Daniel P. Blanchard, Susan N. Parish, Jamie Fleenor, Andrew Fire

104. Investigation of the neuronal function of a dsRNA processing protein
     Whitney Benz, Renee Baran

105. An odr-11 mutation reverses AWC-mediated butanone responses from attraction to avoidance
     Makoto Tsunozaki, Cori Bargmann

106. Identifying regulators of neuronal plasticity in the olfactory adaptation behavior of C. elegans
     Jin I. Lee, Hyun U. Kim, Ty Swartzlander, Noelle L’Etoile

107. Polyunsaturated Fatty Acids Modulate TRPV-dependent Chemosensory Signaling in vivo
     Amanda Kahn-Kirby, Jennifer Watts, Jami L.M. Dantzker, John Browse, Cornelia I. Bargmann

108. Signal Integration in Feeding Behavior
     Andy J. Chang, Cori Bargmann

109. Food-seeking behavior in C. elegans is accomplished by switching modes of locomotion and requires AIY interneurons
     Boris Shtonda, Leon Avery

110. The role of identified neurons in the sensorimotor transformation underlying C. elegans chemotaxis
     Tod R Thiele, Shawn R Lockery

111. Nematode sociobiology: mechanisms of gender-specific social behaviors
     Jamie White, Ping Cheng, Baldomero Olivera, Erik M. Jorgensen

112. Evolution of a polymodal neuron: Comparative analyses of ASH mediated behaviours
     Jagan Srinivasan, Paul Sternberg

113. The genetics of acute adaptation to ethanol intoxication in worms
     Jill C. Bettinger, Andrew D. Goldsmith, Armando R. De La Torre, Steven L. McIntire

114. Cholinergic neurotransmission mutants arising from ethanol-sensitivity screens
     Andrew G. Davies, Meredith E. Judy, Tod R. Thiele, Steven L. McIntire

115. Identifying and Characterizing a Mutation Involved in Male Mating Behavior
     Brigitte L LeBoeuf, L Rene Garcia

116. a. Troponin T may act downstream of UNC-103 to regulate spicule muscle contraction in the C. elegans male
     Todd R. Gruninger, L. Rene Garcia

117. b. Control of locomotory behavior in C. elegans male mating
     Allyson J. Whittaker, Gary Schindelmann, Shahla Gharib, Yvonne Hajdu-Cronin, Katherine Liu, Paul Sternberg

117. The Combined UC San Diego/Caltech Quantitative Behavior Analysis System
     Christopher J. Cronin, Zhaoyang Feng, William Schafer, Paul W. Sternberg

118. Tracking Individual Behaviors in a Population
     Rex Kerr, Catharine H. Rankin, William R. Schafer

119. Algorithms for automated analysis of coiled body postures
     Andy Huang, Pamela Cosman, William Schafer

120. C. elegans demonstrates a 12 hour memory that occurs independent of 24 hour long-term memory
     Jacqueline K. Rose, Catharine H. Rankin

121. Reversing the Effects of Isolation on Response to Tap and on Rate of Development
     Susan Rai, Catharine H. Rankin

122. Neurophysiological analysis of sensation
     Michael Ailion, Shawn R. Lockery

123. Molecular analysis of UNC-43 control of neuronal synchrony in Caenorhabditis elegans
     Allyson V McCormick, James H Thomas

124. dec-2 is a novel gene involved in the regulation of the defecation rhythm of C. elegans
     Jeanna M. Wheeler, James H. Thomas

125. Molecular cloning and physiological characterization of the defecation rhythm controlling gene dec-1
     Takayuki Teramoto, Kouichi Iwasaki

126. Identification and characterization of C. elegans genes involved in a conserved ADPKD pathway
     Samuel G. Wittekind, Jinghua Hu1, Maureen M. Barr

127. C. elegans gene M03F4.3 is a probable candidate for expression of dopamine receptor
     Arpy S. Ohanian, Lily Fang, Allan Mah, Robert C. Johnsen, David L. Baillie

128. Localization and trafficking of the C. elegans dopamine transporter in the living nematode
     Paul W. McDonald, Tammy Jessen, Randy D. Blakely

129. Dopamine signaling through D1-like receptors is required for nicotine dependence in Caenorhabditis elegans
     Zhaoyang Feng, Katie Kindt, Megan Palm, Marika Orlov, Anthony Kempf, William R. Schafer

130. A RNAi Screen for Genes Involved in Tolerance to Nicotine
     James F Cregg, Caroline R Craig, Kathleen B Quast, Suchitra Jagannathan, Kevin J Ford, William R Schafer

131. Discrete genetic targets modulate egg-laying behavior in response to serotonin, fluoxetine, imipramine and dopamine
     Catherine M. Dempsey, Scott M. Mackenzie, Andrew N. Gargus, Gabriela Blanco, Ji Ying Sze

132. Evolution of serotonin synthetic enzyme genes and the patterning of serotonergic neurons in Caenorhabditis and other nematodes
     Curtis M. Loer

133. Serotonin receptors involved in the regulation of pharyngeal pumping and isthmus peristalsis
     Robert J Hobson, Vera M Hapiak, Richard W Komuniecki

134. Environmental Stress and the Genetic Pathways that Regulate Serotonin Levels
     Anahid E. Powell, Ji Y. Sze

135. The Caenorhabditis elegans multiple PDZ domain containing protein, MPZ-1 is involved in the assembly/localization of signaling complexes that include GPCRs and DAF-18 (PTEN)
     Li Lin, Vera M. Hapiak, Hong Xiao, Katherine Smith, Richard W. Komuniecki

136. A Caenorhabditis elegans multi-PDZ domain protein (C52A11.4, MPZ-1) appears to be involved in the synaptic localization of multiple heptahelical receptors
     Hong Xiao, Katherine Smith, Vera M. Hapiak, Li Lin, John Plenefisch, Richard Komuniecki

137. A Putative Transporter Related to NRF-6 and NDG-4 is Required for Amphetamine Sensitivity in C. elegans.
     Miles Trupp, Steven L. McIntire

138. Unraveling the functions of acetylcholine receptors in the worm using RNAi
     Michael Jensen, Michael M. Francis, Andres V. Maricq

139. Genetic Analysis of Gain of Function Acetylcholine Receptors
     Loren Jack, Mike Francis, A. Villu Maricq

140. Accessories to Touch: The Roles of MEC-2 and MEC-6 Studied with Single Channel Recordings
     Austin L Brown, Miriam B Goodman

141. Claudin-like Caenorhabditis Protein-3 a putative Voltage Gated Calcium Channel gamma subunit
     Katya V. Melnik-Martinez, Stefan Herlitze, William R. Schafer

142. DEG/ENaCs Form a Sensory Mechanotransduction Channel Complex in C. elegans Touch Receptor Neurons
     Robert O’Hagan, Martin Chalfie, Miriam B. Goodman

143. unc-58 encodes a member of the TWIK potassium channel family which may have altered selectivity for potassium
     Monika Tzoneva, James H. Thomas

144. Improving Ion Channel Drug Discovery with a C. elegans HTS Screen
     T. Kaletta, R. Zwaal, S. Wuyts, N. Dewulf, G. Nys, S. Turconi, K. van Leemput, V. Lambert, T. Bogaert and G. Plaetinck

145. Identifying Genes Required for Glutamatergic Neurotransmission
     Penelope J. Brockie, Jann Gardner, Andres V. Maricq

146. RPM-1 regulates neuron specific gene expression.
     Joseph Watson, Steve Von Stetina, Peter Roy, Stuart Kim, David M. Miller, III

147. Characterization of the vertebrate tomosyn homolog Tom-1 in C. elegans synapses
     Elena O. Gracheva, Andrea M. Holgado, Robby Weimer, Janet E. Richmond

148. Searching for new genes that regulate synapse development
     Ya Dai, Jonathan Kniss, Yishi Jin

149. Characterization of C. elegans Synapsin, SNN-1
     David Madsen, Michael Francis, A. Villu Maricq

150. Forward genetic analysis of synaptic specificity in C. elegans
     Daniel L Chao, Kang Shen

151. Identifying interacting partners of SYD-1, a presynaptic protein that regulates synapse formation
     Yanli Hou, Hidenori Taru, Yishi Jin

152. Ordering Steps in Regulated Exocytosis in C. elegans
     Christopher E. Hopkins, Marc Hamerland, Shawn Olsen, Eric Jorgensen

153. An investigation of synaptic vesicle transport and maturation
     Heather M. Brown, Dana T. Byrd, Alexandr Goncharov, Yishi Jin

154. Genetic mapping of tba-1(ju89) suppressors
     Lester Laddaran, Luciana Yoshiyasu, Whitney Benz, Yishi Jin, Renee Baran

155. Regulation of a novel MAP kinase cascade by RPM-1 is required for synapse development
     Katsunori Nakata, Benjamin Abrams, Brock Grill, Gloriana Gallegos, Alexandr Goncharov, Xun Huang, Yishi Jin

156. Coordination of pre- and post-synaptic maturation in the egg-laying circuit
     Matthew P Klassen, David A Craig, Kang Shen

157. Mutations in two different genes suppress Unc-34 cell migration and axon outgrowth defects
     Pam Vanderzalm, Mike Hurwitz, Laird Bloom, Bob Horvitz, Gian Garriga

158. Investigations into the mechanisms of SAX-3 mediated axon guidance
     Jason R Kennerdell, Joe Hao, Cori Bargmann

159. The Achaete-scute-like transcription factor, HLH-3, is required for normal egg-laying behavior in C. elegans
     Ryan T. Doonan, Barbara Conradt, Aixa Alfonso

160. Regulation of GABAergic motor neuron fate specification by the sumoylation pathway and chromatin modifying factors
     Julie A. McCleery, James Y. -J. Meir, Chris Li, Yishi Jin

161. Asymmetric Olfactory Neuron Cell Fate Determination
     Miri K. VanHoven, Sarah Bauer Huang, Cori I. Bargmann

162. A forward genetic screen for new genes that regulate asymmetric neuroblast divisions in C. elegans
     Karla Gutierrez, Shaun Cordes, Gian Garriga

163. Two new genes that may work with ham-1 and pig-1 to regulate asymmetric neuroblast divisions in C. elegans
     Shaun Cordes, Gian Garriga

164. Phenotypic characterization of egg-1, a gene required for fertilization
     Pavan Kadandale, Allison Stewart, Barth Grant, Andrew Singson

165. Effects of sperm competition on genetic diversity in experimental populations of C. elegans
     Craig W. LaMunyon, Asher Cutter

166. The Myt1 ortholog in C. elegans is essential for oocyte maturation
     Bonnielin Sceurman, Anna Burrows, Andy Golden

167. The X Chromosome Counting Mechanism of C. elegans Utilizes Multiple X-signal Elements to Determine Sex
     Chin Yee Loh, John Gladden, Jennifer Powell, Barbara J. Meyer

168. The C. elegans ONECUT homologue ceh-39 is an X-Signal Element
     John Gladden, Barbara Meyer

169. The Autosomal Signal in C. elegans Sex Determination
     Margaret M. Jow, Jennifer R. Powell, Barbara J. Meyer

170. The role of PAZ/PIWI domain proteins in the sex-determination/dosage compensation pathway
     Katlin B Massirer, Amy Pasquinelli

171. More on C. briggsae sex determination mutants
     Carlos Carvalho de Egyido, Danielle F. Kelleher, David B. Pilgrim, Eric S. Haag

172. Suppressors of the male gonadal sex-determining gene fkh-6
     Andrea K. Kalis, Annie B. Thompson, Weiru Chang, Andrew E. Schneider, David A. Zarkower

173. Analysis of MAP kinase phosphorylation sites in the C. elegans transcription factor LIN-31
     Catherine A. Mastroieni, Corey A. Morris, Leilani M. Miller

174. Characterization of genes involved in cell fate patterning and/or differentiation in secondary vulval lineages
     Jolene S. Fernandes, Paul W. Sternberg

175. Heterochronic transcription factor lin-29 and coordination of vulval morphogenesis
     Ted O. Ririe, Bhagwati Gupta, Paul W. Sternberg

176. Identification and analysis of several genes involved in Pn.p cell generation and vulval development
     Kiyokazu Morita, Lei Ding, Andy Spencer, Keiko Hirono, Sean Keenan, Min Han

177. A physiological role for let-23/EGFR in C. elegans growth
     Cheryl Van Buskirk, Paul Sternberg

178. The C elegans nuclear receptor gene nhr-25 regulates epidermal cell development
     Zhe Chen, Dennis Eastburn, Min Han

179. Spicule Development & Signal Transduction Specificity
     Adeline Seah, Shahla Gharib, Paul Sternberg

180. cGMP signaling regulates the body size of C elegans
     Manabi Fujiwara, Hiromitsu Ohta, Yasumi Ohshima, Steven L. McIntire, Takeshi Ishihara

181. Characterisation of a Notch signaling pathway homolog required for polarizing the B cell division in C. elegans
     Carrie L. Jones, Helen M. Chamberlin, David L. Baillie

182. Automating cell lineage determination and single-cell expression analysis in C. elegans embryos
     John Isaac Murray, Zhirong Bao, Robert H. Waterston

183. Function and regulation of two posterior-group Hox genes, nob-1 and php-3
     Zongzhi Liu, William Bill Wood

184. Cis- and Trans- control of excretory cell specific expressions in Caenorhabditis elegans
     Zhongying Zhao, David Leonard Baillie

185. Conservation and architecture of the mesendoderm gene network
     Wendy WK Hung, Gina Broitman-Maduro, Tan-Hui Lin, Morris F Maduro

186. Is there a direct interaction between POP-1 and MED-1?
     Tan-Hui Lin, Gina Broitman-Maduro, Wendy WK Hung, Morris F Maduro

187. Mapping two Suppressors of the pharyngeal morphogenesis mutant, pha-1
     Bethany L. Johanson, Xiaohui Qui, David S. Fay

188. Elucidating genetic partners: an RNAi screen with pha-1, and mapping slr-2
     John David K Mc Enerney, Aaron M Bender, David S Fay

189. ZEN-4/MKLP and CYK-4/RhoGAP are required to Polarize the Foregut Epithelium
     Jennifer R. Saam, Mike Portereiko, Noah Jenkins, Susan E. Mango

190. Molecular and Genetic Screens for Regulators of Pharynx Development
     Indra Raharjo, Michelle Theam, Jeb Gaudet

191. ARI-1, a ubiquitin ligase involved in C. elegans pharyngeal development
     Xiaohui Qiu, Iqbal Ahmed, Bethany L. Johanson, David S. Fay

192. Genetic analysis of the C.elegans pax-6 locus, and cellular and high throughput approaches towards PAX-6 target genes
     Hediye Nese Cinar, Andrew D. Chisholm

193. mor-3 encodes a C. elegans death-associated protein kinase (DAP kinase) that functions in post-embryonic epidermal morphogenesis
     Amy Tong, Sarah Moseley, Alexandr Goncharov, Yishi Jin, Andrew Chisholm

194. lin-35/Rb cooperates with the SWI/SNF complex to control C elegans Larval Development
     Mingxue Cui, David S. Fay, Min Han

195. vab(ju432), a new locus involved in epidermal elongation and muscle attachment
     Ryann E Swale, Mei Ding, Andrew D Chisholm

196. The extracellular matrix protein F-spondin is essential for muscle attachment and epidermal elongation
     Wei-Meng Woo, Mei Ding, Jian Cao, Christie Emigh, Chris Suh, Yishi Jin, Andrew D. Chisholm

197. Characterisation of the essential rol-3 signalling pathway and its suppressors, srl-1 and srl-2
     Martin R Jones, Rebecca Newberry, David L Baillie

198. Molecular Characterization of C. elegans dpy-14, a Collagen Gene with Homology to the Human Collagen III Gene COL3A1
     Marco Gallo, Allan K. Mah, Robert C. Johnsen, David L. Baillie

199. Discovering glo-2: Identification of a gene necessary for lysosome biogenesis
     Elizabeth X. Kwan, Beverley M. Rabbitts, Lena K. Schroeder, James R. Priess, Greg J. Hermann

200. Molecular and genetic analysis of a Rab GTPase necessary for lysosome biogenesis
     Lena K. Schroeder, Aaron M. Kershner, Caroline A. Hieb, James R. Priess, Greg J. Hermann

201. Mechanisms of Polycystin Ciliary Localization in C. elegans
     Young-Kyung Bae, Maureen M. Barr

202. MGM-1 mutant induces mitochondrial inner membrane division
     Takayuki Kanazawa, Mauro D. Zappaterra, Ashley P. Wright, Karolyn F. Buttle, Carmen A.Mannella, Kent L. MacDonald, Alexander M. van der Bliek

203. Deciphering Role of Endophilin Related Protein 1 (erp-1) in C.elegans
     Shilpa S.Gandre, Alexander M.van der Bliek

204. Identification of Novel Mitochondrial Division Proteins
     Brian P. Head, Alexander M.van der Bliek

205. Identification and phenotypic analysis of five genes involved in the control of cell division in the endoderm
     Isabella Mengarelli, Cricket G. Wood, Leukena Cheam, Ravi S. Kamath, Andrew G. Fraser, Julie Ahringer, Joel H. Rothman

206. cdc-14 regulates cki-1 to control cell-cycle arrest
     R. Mako Saito, Audrey Perreault, Bethan Peach, John S. Satterlee, Sander van den Heuvel

207. Functional Interactors of MDF-1, a spindle assembly checkpoint component in Caenorhabditis elegans
     Maja Tarailo, Ann M. Rose

208. A novel role for phg-1 in rate of somatic development
     Thevagi Satkunendran, W. Brent Derry

209. Regulation of Asymmetric LET-99 Localization in C. elegans Embryos
     Jui-ching Wu, Lesilee S. Rose

210. The role of the spn-2 gene in spindle positioning
     Leah R. DeBella, Wei Li, Lesilee S. Rose

211. Role of LET-99 in G protein signaling during spindle positioning in embryos
     Dae Hwi Park, Meng-Fu Tsou, Lesilee S. Rose

212. Screen for TLK-1-Interacting Proteins
     Yeh Chan-Hsien, Wu Yi-Chun

213. Identification and Characterization of Separase Cofactors in C. elegans
     Christopher T. Richie, Bonnielin Sceurman, Barry Chestnut, Andy Golden

214. Characterization of bs7, a mutation affecting centrosome duplication and microtubule organization in C. elegans
     Addepalli MK, Kevin F. O’ Connell

215. The C. elegans condensin II complex maintains chromosome resolution in late meiotic prophase and promotes chromosome segregation in meiosis I and II
     Aaron F. Severson, Raymond C. Chan, Barbara J. Meyer

216. Coordinating homolog pairing and synaptonemal complex assembly in meiosis
     Natasha L. Miley, Enrique Martinez-Perez, Kentaro Nabeshima, Amy J. MacQueen, Anne M.Villeneuve

217. Chromosome segregation during oocyte meiosis
     Sarah M. Wignall, Anne Villeneuve

218. Functional Interactions with Dog-1
     Jillian L. Youds, Ann M. Rose

219. Biological Function of G/C-tracts in Caenorhabditis elegans Genome
     Yang Zhao, Ann Rose

220. Telomere length measurement in C. elegans by Single Telomere Length Analysis
     Iris Cheung, Mike Schertzer, Agnes Baross, Ann M. Rose, Peter M. Lansdorp, Duncan M. Baird

221. Elucidating the Genetic Network Controlling Chromosome Stability in C. elegans
     Jelena Kisin-Rajlic, W. Brent Derry

222. UNC-83 has a KASH domain required for nuclear envelope localization and nuclear migration
     Amy Anderson, Matthew McGee, Daniel A Starr

223. Genetic screens for nuclear migration and anchorage components
     Karin Warltier, Lita Stephenson, Daniel A. Starr

224. Linker Cell Migration
     Mihoko Kato, Paul W. Sternberg

225. Identification of targeting domains and transport mechanisms involved in the localization of cilia proteins
     Jenny C. Schafer, Bradley K. Yoder

226. Two Anterograde IFT-motors cooperate to drive two pathways of Intraflagellar Transport
     Joshua J. Snow, Guangshuo Ou, Amy L. Gunnarson, Maria Regina Sagullo Walker, H. Mimi Zhou, Ingrid Brust-Mascher, Jonathan M. Scholey

227. Characterization of the novel monoclonal antibody F2-P3E3, a predicted apoptotic marker in Caenorhabditis elegans
     Robin J. Eisenhut, James R. Priess, Greg J. Hermann

228. ced-10 Mutations Reduced Numbers of Persistent Cell Corpses in Strong ced-2, ced-5, and ced-12 Mutants
     Ruei-Ying Tzeng, Li-Chun Cheng, Yi-Chun Wu

229. Structural and Functional Analysis of PSR-1 in C. elegans
     Pei-ken Hsu, Ming-chia Lee, Yi-chun Wu

230. Functions of the Outer Mitochondrial Membrane Protein CED-9
     Frederick J Tan, Andrew Z Fire, R Blake Hill

231. Suppression of CED-3-Independent Programmed Cell Death In C. elegans
     Thomas A. McCloskey, Chiou-Wei Tsai, Vebjorn Ljosa, Peter Bowers, Ambuj Singh, Joel Rothman

232. Functional Characterization of a Putative Apoptotic Suppressor, tfg-1, in C. elegans
     Ling Chen, Tom McCloskey, Joel H. Rothman

233. An RNAi Screen for CED-4-Dependent Lethal Genes
     Jeremy Wickenheiser, Joel H. Rothman

234. Identification of novel compounds that protect DA neurons against 6-OHDA induced cell death
     Charles Nichols, Marketa Marvanova, Mika Garrett, Richard Nass

235. Heavy metals and a pesticide confer DA neuron cell death and amplify the neurodegeneration in C. elegans models for Parkinson’s disease
     Marketa Marvanova, Michelle Fullard, Richard Nass

236. Application of a novel aggregating derivative of GFP to investigate the general cellular response to protein aggregation
     Brian Hiester, Gin Fonte, Jey Yerg, Jmil Ferguson, Chris Link

237. Hypoxic Preconditiong Protects neurons and muscles from hypoxic cell death
     Nupur Dasgupta, C .Michael Crowder

238. Responses to Oxygen Deprivation in C. elegans
     Dana L. Miller, Mark B. Roth

239. Respiration and Aging
     David Z Cristina

240. Reduction in cep-1 expression increases lifespan
     Oge Arum, Tom Johnson

241. Feed-forward regulation of the DAF-2 pathway by two opposing insulins
     Coleen T. Murphy, Cynthia Kenyon

242. The daf-2 insulin signaling pathway independently regulates ageing and immunity
     Eric A. Evans, Man-Wah Tan

243. RNAi screen of C. elegans’ innate immune response to Bacillus thuringiensis toxin Cry5B
     Kathleen A. Andrews, Danielle L. Huffman, Raffi V. Aroian

244. The mapping and identification of a gene associated with resistance to a specific crystal protein produced by Bacillus thuringiensis
     Brad Barrows, Raffi Aroian

245. Identification of Salmonella typhimurium genes required for persistence in the gut of C. elegans
     Rosanna Alegado, Stanley Falkow, Man-Wah Tan

246. Analysis of a C. elegans Mutant that is Hypersensitive to the Pore-Forming Bacterial Toxin Cry5B
     Larry J. Bischof, Raffi V. Aroian

247. Induction of Drosophila Immune Response by the Parasitic Nematode Heterorhabditis bacteriophora
     Michelle Rengarajan, Todd Ciche, Takao Inoue, Paul W. Sternberg

248. Novel Growth Conditions for Culturing C. elegans in Microgravity
     Thomas Fahlen, June Sunga, Kevin Sato, Melissa Kirven-Brooks, Debra Reiss-Bubenheim

249. Spaced-Out Worms
     Yang Zhao, Jillian Youds, Maja Tarailo, Iris Cheung, Kenneth Lai, Sanja Tarailo, ManTek Yeung, Ann Rose

250. Defective Embryonic Development in lis-1 Mutants of Caenorhabditis elegans
     Ned Buttner, H. R. Horvitz, Craig P. Hunter

251. A C. elegans model for Niemann-Pick Type C2 Disease
     Gemma Brown, Jie Li, Samuel Lee, James H. Thomas

252. Biochemical Characterization of the C. elegans Nuclear Hormone Receptor NHR-49
     Stefan Taubert, Marc Van Gilst, Keith R. Yamamoto

253. Genetic Characterization of the delta-9 Fatty Acid Desaturases of C. elegans
     Trisha J Brock, John A Browse

254. Analysis of the Neuroendocrine Regulation of Fat Content
     Brendan Mullaney, Elizabeth "Zib" Greer, E. Lorena Mora-Blanco, Anne Slavotinek, Kaveh Ashrafi

255. Large-scale Analysis of Fat and Metabolic Networks
     Kevin Jones, Amanda Habel, E. Lorena Mora-Blanco, Marc Van Gilst, Kaveh Ashrafi

256. Activation of the body wall muscle of the C. elegans fat-3 mutant by DHA
     S. Luke Hillyard, Raymond C. Valentine, J. Bruce German